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The primary goal of treatment should extend beyond weight loss to encompass the preservation of lean mass, improvement in metabolic health, and long-term prevention of obesity-related complications [7]
Lancet Diabetes Endocrinol 2025;13(1):15-28
All procedures were approved by the Animal Care and Use Committee of the Shanghai Medical College of Fudan University and were performed according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals
Clinicians should monitor patients for potential adverse effects including pancreatitis (severe, persistent abdominal pain), gallbladder disease (right upper quadrant pain), diabetic retinopathy complications (especially with rapid glucose improvement), acute kidney injury with dehydration, and hypoglycemia when combined with insulin or sulfonylureas
Youre going from a dual-receptor medication to a single-receptor one, and for many patients, that difference is noticeable
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