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Single-target compounds such as Epithalon (Epitalon) isolate telomerase and circadian pathways, while SS-31 (Elamipretide) focuses on mitochondrial function

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Beside methionine oxidation and protein N-terminal acetylation, following cysteine modifications were considered as variable modifications: sulfinic acid, sulfonic acid N-ethylmaleimide, glutathione, disulfide (-H)

Vitamin B12 (Cobalamin) is an essential nutrient that plays a key role in red blood cell production, nerve function, and energy metabolism

Then, the cells were seeded onto six-well plate, cultured for 24 h and imaged with an inverted microscope (IX83, Olympus)

doi: 10.1111/nyas.13736