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The flow diagram of the literature search process is presented in online Supplementary Fig

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Even though the definitive role of GSH imbalance in PD is still debated, the efficacy of therapeutic antioxidant and anti-inflammatory agents in PD models underscores the potential of targeting this pathway to halt disease progression (Leathem et al., 2022)

Healing Properties: Unlike retinoids, which can initially compromise the skin barrier, copper peptides actually enhance wound healing and barrier function

FDA's 2024 review states the mechanism of action is still unknown, which limits how confidently any specific physiological effect can be predicted in humans