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Scientific Activity In biochemical and cell models, 5-AMINO-1MQ inhibits NNMT, reducing methyl transfer from S-adenosylmethionine to nicotinamide and altering downstream methyl-donor and nicotinamide metabolite pools

And the answer is both simple and nuanced

Those who deal with low energy or a sluggish metabolism

In fact, one study noted 1,0002,000 mg per day of NR caused no harmful effects in humans, aside from some mild side effects in a few participants

Thats really good since its hard to loose the last 10

Age, sex, BMI, diabetes status, genetic markers, microbiome composition, and lifestyle factors all influence outcomes