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We additionally summarize the evidence by domain and certainty level in a structured Supplementary Table 6, explicitly separating relatively robust short-term metabolic evidence from more exploratory reproductive and periconception safety findings

Costs vary depending on medication and dosage

Curr Pharm Des 2014;20:2669-2683

Bile is produced by the liver and stored in the gallbladder to aid fat digestion

To determine the gel regions to be excised for MS analyses, we used an overlay of the color image of pre-stained molecular weight (Mr) standards and the ECL signal (Supplementary Figure S1B)

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