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This dual-phase pharmacokinetic profile means the blend delivers immediate pulsatile growth hormone release via ipamorelin's ghrelin receptor agonism, followed by sustained growth hormone-releasing hormone receptor activation from tesamorelin

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Biochem Biophys Res Commun 291:13021308 Yasuda N, Inoue T, Nagakura T et al (2002) Enhanced secretion of glucagon-like peptide 1 by biguanide compounds

Catagen phase : A brief transition where growth stops and the hair follicle begins to shrink