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Options include compounded semaglutide and compounded tirzepatide , along with non-GLP-1 alternatives like metformin, naltrexone, and bupropion

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While most back pain during GLP-1-based therapy is likely unrelated to the medication and may resolve with conservative management, certain presentations warrant prompt medical evaluation

Similarly, oral supplementation of -tocopherol in mice inhibits iron accumulation and modulates Nrf2 expression, leading to the depletion of hepatic iron stores and enhanced iron efflux through FPN, further strengthening the antioxidant response (65)