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As shown in Figure 1 , reducing dietary TMAO precursor intake is a promising strategy for lowering the risk of CVD due to the high amounts of trimethylamine (TMA) and TMAO generation by choline-induced gut flora (28, 29)

Contributions of bloodbrain barrier imaging to neurovascular unit pathophysiology of Alzheimers disease and related dementias

PMID: 34072834

Animal studies have revealed evidence of teratogenicity, fetotoxicity, and abortion when this drug was administered in pregnant animals during organogenesis at clinically relevant exposures based on AUC

Group sizes ranged from four to seven animals

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