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LDL (commonly referred to as the bad cholesterol) can transport cholesterol to arterial walls, contributing to the development of atherosclerosis (hardening and narrowing of arteries) and cardiovascular disease

The brain capillary pericytes respond to neuronal and astrocytic signals by regulating intracellular Ca 2+ and K + , leading to either hyperpolarization or depolarization, thereby influencing CBF

(PubMed) Tucker KL, Qiao N, Scott T, Rosenberg I, Spiro A, 3rd

It has protein Protein matters because reduced appetite can make it harder to eat enough

Henquin JC (2009) Regulation of insulin secretion: a matter of phase control and amplitude modulation

Losing 7% or more (17.5 lbs for a 250 lb person) also shows a reduction in inflammation and improved health of liver cells