The severity and duration of these headaches vary widely based on your hydration status, dose escalation speed, and individual metabolic sensitivity
I long recognized that people would come to me saying, "I ran all the labs and everything looks fine." And I'd look at the same labs and see early insulin resistance
Olanow, C

Nausea and digestive discomfort Eat three balanced meals a day based on whole foods Choose easy-to-digest foods during the first few weeks, such as scrambled eggs, white fish, and cooked vegetables Stay well hydrated between meals (aim for 2 litres daily) Limit the intake of ultra-processed foods and takeaways Consider ginger tea or supplements, which may help reduce nausea in some people Fatigue Ensure adequate protein intake at each meal Include iron-rich foods like red meat and spinach alongside vitamin C sources Maintain consistent sleep habits Dont skip meals, even if your appetite is reduced Changes in appetite Maintain three balanced meals a day based on whole foods, even if hunger is low Include a protein-rich food at each meal, roughly a palm-sized portion Include plenty of non-starchy vegetables to maximise the nutrient density of meals Plan healthy snacks for times when hunger might increase Most transition-related side effects resolve within 2-4 weeks as the body adjusts to the new medication

Schober P, Loer SA, Schwarte LA
Vitamin B12 injections are often administered weekly