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The court agreed, finding that while the label cautioned against using multiple GLP-1s together, it did not explicitly instruct physicians to avoid all other drugs

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Semaglutide (marketed as 'Ozempic' and 'Wegovy') and the dual-agonist Tirzepatide ('Mounjaro' and 'Zepbound') are some of today's most talked-about medications, given their unprecedented clinical efficacies across both weight loss and T2D management

However, the model system used here is not appropriate to extrapolate to this phenomenon and further work is needed to evaluate the relevance of the mechanisms defined in HepG2 cells to the clinical setting

In trial settings, it is given as a once-weekly subcutaneous injection into the abdomen or outer thigh, following a gradual dose escalation protocol