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In a phase 2b trial, 392 patients with bridging fibrosis or compensated cirrhosis (F3-F4) were randomized to receive placebo, selonsertib 18 mg, cilofexor 30 mg, or firsocostat 20 mg, alone or in two-drug combinations, once daily, for 48 weeks

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But this complex interplay of hormonal signals is precisely why we need to look closely at its effects on systems beyond metabolism, like the heart

These services, available through GP referral, offer group or individual sessions over 1224 weeks