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The peptide's actin-sequestering activity proves particularly important for endothelial cell migration, with studies showing TB-500 significantly enhances endothelial cell migration rates and tube formation in angiogenesis assays while promoting the formation of stable, mature blood vessels with appropriate pericyte coverage

These results suggest that, despite the expression of LAT1 on the blood-brain barrier (BBB), LAAM GSH-CQDs do not accumulate in the brain without tumors

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These findings remain research-context findings

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