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The difference appears in convenience

Two types of medications for ulcers and gastric reflux proton-pump inhibitors, such as omeprazole (Prilosec) and lansoprazole (Prevacid), and H2 blockers like cimetidine (Tagamet), famotidine (Pepcid), and ranitidine (Zantac) inhibit the release of stomach acid necessary to free dietary vitamin B12

[DOI] [Google Scholar] Failla M., Floresta G., Abbate V

(2025, May 22)

Bull Exp Biol Med 165:746750 Fernley HN (1971) Mammalian alkaline phosphatases Enzymes 4:417447 Foley MH, OFlaherty S, Barrangou R et al (2019) Bile salt hydrolases: gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

Vitamin B12 helps calm irritated skin, especially when the skin barrier is compromised