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a There is significant heterogeneity for FBG (I 2 = 88.5%), Insulin (I 2 = 96.5%), HbA1C (I 2 = 90.5%) and HOMA-IR (I 2 = 98.1)

World Journal of Gastroenterology

Anemia. National Library of Medicine, StatPearls Publishing, 8 Aug

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Patients treated with semaglutide typically lose a few pounds in the first week and will continue to lose weight

Moreover, the majority of these early non-responders (53-70%) fail to achieve clinically meaningful weight loss of 5% after six months of treatment