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In prediabetes, metformin has evidence for delaying progression to type 2 diabetes in selected higher-risk groups, such as younger adults with higher body weight or people with a history of gestational diabetes

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TM conceived and designed the study, conducted experiments, interpreted the data, and wrote the manuscript

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Hiccups are not a documented side effect in major semaglutide clinical trials or FDA labeling, though anecdotal reports exist online

Phys Rev E 80:031908