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In November 2021, Health Canada approved Wegovy, a higher-dose formulation of semaglutide specifically indicated for chronic weight management in adults with obesity (BMI 30 or greater) or overweight (BMI 27 or greater) with at least one weight-related comorbidity

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[DOI] [Google Scholar] 72.FDAUS Food & Drug Administration FDA Approves Treatment for Serious Liver Disease Known as MASH

Patano and colleagues suggest that this decrease in energy availability might compromise osteoblast activity and bone remodeling in an age-related manner [152]