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Concomitantly, water influx causes matrix swelling, rupture of the rigid OMM and release of apoptogenic proteins sequestered in IMS although, apoptotic cell death under MPT is inhibited due to energetic failure and ATP exhaustion and oxidative stress-mediated caspase inactivation

Garca-Fernndez, A., Aznar, E., Martnez-Mez, R

Unda SR, Villegas EA, Toledo ME, Asis Onell G, Laino CH

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Sulforaphane attenuated these components of oxidative stress and neuroinflammation, reducing autism-like behaviors to control levels

Samples were then washed x3 with cold argon-purged 50 mM HEPES buffer (pH 7.5) and immediately treated by either Procedure A with 5 mM IAM-TPP or Procedure B with 5 mM IAM for 30 min at RT protected from light