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The best-characterized effects of Se deficiency on sperm include significant loss of motility, midpiece breakage, and increased sperm shape abnormalities (mostly with an abnormal sperm head or bent tail, hairpin-like tail, and an increased percentage of tailless and headless sperms) (85)

Dipeptidyl peptidase-4 (DPP-4) inhibitors have emerged as an essential class of oral hypoglycemic agents for T2DM management

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Do not skip doses or discontinue therapy without medical guidance, as weight regain commonly occurs after stopping GLP-1 medications