A.Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to -glucosidase inhibition (acarbose) in Type 2 diabetic patients
Some foaming is normal, but excessive or persistent bubbling warrants caution
Maiti A, DiNardo CD, Wang S, Jorgensen J, Kadia TM, Daver NG, Short NJ, Yilmaz M, Pemmaraju N, Borthakur G, Bose P, Issa GC, Ferrajoli A, Jabbour EJ, Jain N, Garcia-Manero G, Ohanian M, Takahashi K, Montalban-Bravo G, Masarova L, Burger J, Thompson PA, Verstovsek S, Sasaki K, Andreeff M , Rausch CR, Montalbano KS, Pierce S, Kantarjian HM, Konopleva MY, Ravandi F
Subcutaneous injection produces a half life closer to three hours because the peptide enters circulation gradually through capillary absorption, bypassing immediate hepatic degradation
Most patients use lipotropic injections as an adjunct to diet, exercise, and/or GLP-1 medications
No UK marketing authorisation was identified