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It is a critical co-factor in mitochondrial electron transport and an endogenous antioxidant, has garnered significant attention as a potential therapeutic agent for PD

Response: We understand commenters' concern regarding the timing around removal of these measures and the confusion and burden this may impose on hospitals and ASCs that have already submitted CY 2024 quality data

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This result is consistent with our previous MR analysis, suggesting that DKK3 may accelerate cataract development under oxidative stress by promoting apoptosis or regulating signal transduction

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