Tissue specific genetic manipulations were performed using the Gal4-UAS system described previously 42
This may identify the so-called parallel or non-parallel healing actions, with the final end result, positive (fistula closing) or negative (fistula remains open) (Skorjanec et al., 2009)
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Rat doses of 10 mcg/kg translate to roughly 1.6 mcg/kg in humans, which falls within the commonly compounded dose range of 200-500 mcg/day for a 70 kg individual
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