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The truth is that GLP-1s dont directly cause fatigue, but they can contribute to tiredness for a few different reasons related to how they affect your metabolism and digestive system

If you wear dentures, changes in the way they fit may signal swelling or tissue changes related to your medication

In large clinical trials, thyroid function tests generally remained stable during treatment

Its benefits often extend beyond the number on the scale because weight management can also support overall wellness, confidence, and long-term health habits

Miftaraj, J

This may happen if your diet or activity levels need adjustments or if your metabolism is slower than expected