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Four isoforms of PKs have been identified: liver-type PK (PKL), red blood cell PK (PKR), and muscle isozymes M1 and M2 (PKM1 and PKM2, respectively) (39)
Med Sci Monit 23:55995612
Here are some common causes: Dietary deficiency, mainly in vegans and vegetarians Pernicious anemia, an autoimmune issue with intrinsic factor production Gastric disorders, like atrophic gastritis or gastrectomy Malabsorption conditions, including Crohns disease and celiac disease Certain medications, like proton pump inhibitors and metformin Signs and Symptoms Requiring Medical Intervention Its important to know the signs of vitamin B12 deficiency
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10.1016/j.lfs.2021.119921 49 LiN.CuiX.MaC.YuY.LiZ.ZhaoL.et al (2022a)
