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Discussion The phase 2 trial of retatrutide vs placebo investigated the safety and efficacy of retatrutide in adults with obesity or overweight [11,12]

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25 Although data from clinical studies on liraglutide revealed a 7% increase in serum amylase and a 31% increase in serum lipase in patients after four weeks of GLP-1 receptor agonist treatment compared with placebo, the increased levels reverted to normal once therapy was discontinued and did not predict acute pancreatitis onset

Sajobi 12 , Cathy Son 13 , Kara Schick-Makaroff 14 , Hubert Wong 15 , Bruno D

Jeffrey Egler, Nooms chief medical officer

The Danish drugmaker found that liraglutide showed outstanding weight-reducing effects when used as a diabetes treatment (Victoza) and turned it into an obesity treatment