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By substituting key amino acid residues, scientists have reduced susceptibility to enzymatic degradation, thereby extending the half-life of the molecule in experimental systems

During this process, they secrete IL-10 and TGF-, reinforcing an anti-inflammatory feedback loop (121)

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10% were collected for protein analysis, the remaining beads were resuspended in Trizol (Life Technologies), and RNAs were extracted according to the manufacturers protocol

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(PubMed) Lundblad C, Grande PO, Bentzer P