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Oxidative stress in inflammation-based gastrointestinal tract diseases: challenges and opportunities

PMID: 23825127 | doi:10.1210/en.2012-2175 Sattler FR

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While yerba mate may support overall wellness through caffeine and polyphenol content, genetic variants in GLP1R, GIPR, FTO, and MC4R pathways reveal whether you may benefit more significantly from targeted GLP-1 pharmacotherapy

It depends on both copper and zinc as cofactors, but only copper regulates its activity ( 2 O 2 , CuZn-SODs activity is suppressed, via oxidation of His-118 to form 2-oxo-histidine (Uchida and Kawakishi, 1994)

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