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A.AhmedM

IM injection achieves faster initial uptake but produces a shorter duration of action

Exclusion criteria: (1) Patients with abnormal coagulation function [limits: prothrombin time (PT) between 1014 seconds, activated partial thromboplastin time (APTT) between 2540 seconds, and fibrinogen (Fib) levels between 2.04.0 g/L] and immunodeficiency [either primary immunodeficiency (congenital or hereditary conditions leading to impaired immune responses) or secondary immunodeficiency (conditions acquired through HIV infection, chronic immunosuppressive therapy, or severe malnutrition)]

Others need 15 mg to maximize effect

Folate and vitamin B12 levels in an urban elderly population with chronic diseases

every 23 days) is practical, whereas local patients might opt for weekly injections depending on physician preference