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In phase 2 TOPAZ (NCT03921528) and phase 3 SAPPHIRE (NCT05156320) trials, apitegromab treatment improved motor function in patients with spinal muscular atrophy (SMA) 9,16

The 0.25 mg dose isnt designed to cause weight loss just yet, its there to help your body ease into treatment

On further probing Madsen found that the tumours secreted an abundance of GLP-1, which he published in a paper together with Holst and others in 1995 (Blume, Skouv, Larson)

Brain-Gut Axis and Pentadecapeptide BPC-157: Theoretical and Practical Implications

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Learn more GLP-1 medications like Ozempic and Wegovy are changing how the medical system approaches obesity and metabolic disease