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Psychedelic Research in Science and Medicine (PRISM) advised that any decision to down-schedule [MDMA] should include an extensive two-year implementation plan

Many people lose fat more easily, especially in the midsection

However, the pivotal 36-week Phase 2 trial showed a larger range of mean loss, from 9.4% to 14.7%, across doses, confirming robust dose-dependent effects

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Five subjects in the DHT arm (5/24) experienced no AEs (referenced as a 20.8% reduction in Lexarias press release)