Its hard to predict the future, but I think theres real cause for optimism The pipeline of these drugs is massive and the trials to date have been incredibly encouraging
Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety
In this model, employees obtain GLP-1 prescriptions via eMeds telehealth platform (with remote monitoring), and then split the cost of the drugs with the employer at discounted rates
Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N
1113-1124, Mosenzon, O., et al
Occasional nausea is common with GLP-1 RAs, but persistent vomiting (GLP-1 related or not) can deplete electrolytes significantly