GH reports research grants from the Netherlands Organization for Scientific Research (vidi 016.156.445), CardioVascular Research Initiative, European Union and the Klinkerpad fonds, institutional research support from Aegerion, Amgen, AstraZeneca, Eli Lilly, Genzyme, Ionis, Kowa, Pfizer, Regeneron, Roche, Sanofi, and The Medicines Company
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Pharmacological dissection identifies retatrutide overcomes the therapeutic barrier of obese TNBC treatments through suppressing the interplay between glycosylation and ubiquitylation of YAP
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Many cyanobacteria (and microalgae broadly) are safe to eat, though not every strain of cyanobacteria has a GRAS certification.5 Under the GRAS framework, an ingredient has to be demonstrated as safe either through (1) scientific procedures or (2) in the case of a substance used in food prior to January 1, 1958, through experience based on common use in food. For cyanobacteria to be used as a platform for oral GLP-1 delivery, either a GRAS organism like spirulina must serve as the host organism or, if choosing a different species, the manufacturer must prove with adequate in vivo trial data that it is safe to eat
The protocol for this systematic review can be accessed at 2.1 Sources and Search Strategy The PubMed and EMBASE electronic databases were comprehensively searched up to November 1st, 2023
