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GLP-1s seem to offer some benefit in brain health, says McIntyre
Such biomarkers include zonulin, fatty acid binding proteins (FABP), citrulline, glucagon-like peptide (GLP)-2, LPS, LPS-binding protein (LBP) or fecal 1 antitrypsin (AAT), for example
The TRIUMPH programme will investigate retatrutide in people with obesity and the TRANSCEND-T2D programme is investigating retatrutide in people with T2D and overweight/obesity
Published Aug 13, 2025
Significant weight loss from tirzepatide may reduce levothyroxine requirements in some patients, necessitating TSH monitoring at baseline, after substantial weight loss, and every 6-12 months once stable
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