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The pathophysiology of DOX-induced POI is complex, but numerous factors have been proposed to be linked to the onset and development of ovarian dysfunction, including free radical-mediated lipid peroxidation, oxidative stress, mitochondrial malfunction, increased proinflammatory release of cytokines, and granulosa cell apoptosis 12,13,14

Journal of Cosmetic Dermatology [Internet]

It exists more on a continuum

S2CID 25290793

Apoya el metabolismo de nutrientes: El picolinato de cromo colabora con el metabolismo normal de carbohidratos, grasas y protenas, y con la sensibilidad a la insulina, lo que puede favorecer el equilibrio energtico

Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes