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Soon after developing GLP-1s, researchers uncovered a second therapeutic effect that could benefit an even larger patient population: sustainable, clinically meaningful weight loss

5 The Food and Drug Administration has approved Ozempic and Mounjaro to treat diabetes

J Neurochem 71:25102517 Rossato MS, Brilli E, Ferri N, Giordano G, Tarantino G (2021) Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-COV-2 post-infection progress

Retatrutide at 12mg produces an average of 28.7% total body weight reduction over 48 weeks in clinical trials

The standard route for both Retatrutide and GLOW

From Phase 2 to Phase 3: how the story developed The Phase 2 NEJM study (Jastreboff 2023) The modern retatrutide story begins with Jastreboff AM et al., published in the New England Journal of Medicine in 2023 (DOI 10.1056/NEJMoa2301972)