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Note: For complete details, please review product monographs at and regularly review current Health Canada advisories, warnings and recalls at: for the most up to date information.) Table 4: Treatment of B 12 deficiency (adapted from Means 2021) 27 Note: Intranasal administration is generally not used

doi: 10.3390/ijms21124264 87 BaiKLeeC-LLiuXLiJCaoDZhangLet al

Ongoing monitoring is important, particularly for blood pressure and kidney function

The coenzyme is also important for the elongation and desaturation of fatty acids [20, 21], biosynthesis of cholesterol [22], hydroxylation of steroids and other polycyclic molecules including vitamin D [23], drugs metabolism by the cytochrome P450 [24], and ROS generation in phagocytic and inflammatory cell to counteract pathogens [25]

Fortunately, there are other options

10.1089/ars.2018.7678 Antioxid