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Combined with adequate protein intake (widely recommended at 1.2-1.6g per kg of body weight during GLP-1 protocols) and resistance training, the higher dose ranges may actually preserve lean mass better than lower doses, because the energy deficit is being met predominantly through fat oxidation rather than muscle catabolism

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In individuals with SCD, the antioxidant defense system is greatly compromised due to depleted expression and activity levels of antioxidant enzymes (e.g., superoxide dismutase-SOD, catalase-Cat, and glutathione peroxidase-GPx)

I started out with a similar level (after a holiday in the south of France) but with a year plus of taking 2000iu d3 with 90mcg k2 daily it reached over 90

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Get a pea-size amount of tretinoin on your finger