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The clinical and commercial success of ADCs has validated that antibody-mediated targeting can enhance the accumulation of therapeutic payloads at disease sites while mitigating off-target toxicity [214]

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Heavy alcohol use can enhance the hypoglycemic effects of insulin and sulfonylureas, and the Wegovy prescribing information identifies greater hypoglycemia risk when semaglutide is used with insulin or an insulin secretagogue

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10.1038/s41467-022-30559-2 258 ZhuL.WangZ.HanW.XuA