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However, the studies included were of shorter duration (three months) with a limited number of patients and wide confidence intervals [35]

The concept of bioavailability may, in part, also explain why the same dose may cause toxicity by one route (IV) but not the other (smoking)

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The meta-analysis of 21 trials (PIONEER and SUSTAIN) with 12,260 semaglutide users and 14,176 comparators was funded by the Shenzhen Key Medical Discipline Construction Fund