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Here is a breakdown of the main safety concerns around GLP-1 drugs for people with lupus

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Dehydroepiandrosterone (DHEA) is a steroid hormone produced by the adrenal glands, the same glands responsible for cortisol and adrenaline production

This deuterium exchange is in contrast to surrounding amides, which exchange very little if any deuterium after 30 s, and is evidence of a thermodynamically weaker hydrogen bond at this amide