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The application of 100 nM CAP elicited inward currents, indicating CAP-responsive DRG neurons, and these responses were abolished by pretreatment with 100 nM GLP-1(736) by 52% (Fig
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In the stomach, it slows emptying, so food leaves more gradually and the post-meal glucose curve flattens
Systemic side effects observed in retatrutide trials are broadly consistent with the GLP-1 receptor agonist class and include nausea, vomiting, diarrhoea, constipation, decreased appetite, and fatigue
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