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Slower digestive pace can affect: Fullness and appetite : feeling satisfied faster Nausea : particularly when starting or increasing doses Constipation : from slower intestinal transit Diarrhoea : paradoxically, some people experience the opposite Bloating and abdominal discomfort : symptoms many IBS sufferers already know too well

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For instance, if patients present with symptoms such as early hunger or lack of satiety then a GLP-1RA may be appropriate compared with other available treatments that work solely by suppressing appetite or inhibiting fat absorption [23]

Cardiovascular metabolic research investigates lipid profile improvements and potential cardioprotective effects from the combined mechanism