The neuroprotective role of estrogens implies a close regulation of processes such as (i) anti-oxidant activity (Kumar et al., 2010), (ii) DNA repair (Scharfman and MacLusky, 2006), (iv) synaptic plasticity (McEwen and Milner, 2007), and (v) the blood flow to the brain (Zhao and Brinton, 2006
465 Impaired GLP-1 secretion or reduced GLP-1R expression may result in aberrantly heightened sympathetic excitation
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Doctors swear an oath to first, do no harm, and are expected to use treatments supported by evidence or, at minimum, a plausible expectation of benefit outweighing risks
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doi: 10.3389/fnut.2025.1656048 Received 29 June 2025 Accepted 29 August 2025 Published 09 October 2025 Volume 12 - 2025 Edited by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Reviewed by Pooja Yadav, Shree Guru Gobind Singh Tricentenary University, India Yansong Fu, Central South University, China Updates Copyright 2025 Ye, Yuan and Cai