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Presence of other chronic conditions, such as cancer, that may increase the risk of a blood clot

Int J Mol Sci 20:4136

They are likely multifactorial and may involve delayed gastric emptying, altered intestinal fluid secretion, and central nervous system effects on gut function

At a dosage of 3,000 mcg (approximately 10,000 IU), it serves as a reliable source of Vitamin A for individuals who may have low dietary intake or increased nutritional needs

Due to tirzepatide's long half-life (approximately five days) and delayed peak concentration (8-72 hours after injection), symptoms typically reflect steady-state effects rather than immediate post-injection peaks

The risks may be higher for people with a history of blood clots