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It is the same active drug as Mounjaro, but with a different label and weight-loss-focused indication

Compared to native glucagon and GLP-1, retatrutide shows lower potency at GLP-1 and glucagon receptors but higher potency at the GIP receptor

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Pathological manifestations of DPDs usually manifest macrovascular atherosclerosis, as well as microvascular endothelial function impairment, basement membrane thickening, and microthrombosis

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