& Goadsby, P
E.KramersB
People with diabetic retinopathy should be monitored, as rapid improvements in blood glucose control have been associated with worsening of this condition
Seek medical attention if : Bruising is severe, extensive, or disproportionate to the injection New bruises appear spontaneously at non-injection sites Bruising is accompanied by prolonged bleeding, petechiae (pinpoint red spots), or mucosal bleeding (nosebleeds, gum bleeding) Signs of infection develop (increasing pain, warmth, redness, swelling, or discharge) Bruises fail to resolve after 34 weeks Documentation : Keep a record of injection sites and any bruising patterns
2023, Wharton, Sean et al
Continued tirzepatide: Lost an additional 5.5% Total weight loss at 88 weeks: 25.3% 89.5% maintained at least 80% of their weight loss Switched to placebo: Regained weight Total weight loss at 88 weeks: 9.9% Only 16.6% maintained at least 80% of their weight loss This trial demonstrates that tirzepatide works best as ongoing treatment and that stopping medication typically leads to significant weight regain
