Some case studies have even documented reports of toxic thyroid levels due to over-supplementation of ashwagandha (although this appears to be exceedingly rare and other factors seem to be involved as well)
Digestive issues, including nausea, vomiting, and abdominal discomfort, may arise
Frequently Asked Questions Is constipation on GLP-1 medications permanent
And not all studies found the same link, so the evidence is mixed
All structural and pharmacological information presented here is derived from published preclinical and Phase 1-2 clinical trial data
For example, some studies are focusing on older adults, who might prefer a needle-free option, or individuals with severe obesity, to see if they respond differently to sublingual administration