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Free Radic Bio Med 2024;215:3747

[76] Dopamine agonist such as levodopa: One of levodopa's chronic side effects in Parkinson's patients is the "on-off phenomenon" of motor fluctuations - periods of oscillations between "on", where the patient experiences symptomatic relief, and "off", where the therapeutic effect wears off early

10.1016/j.biopha.2021.111475 191 ZhangW.PingJ.ZhouY.ChenG.XuL

Also, reduced glutathione is more sensitive to environmental conditions , so its preservation requires specific processes to prevent degradation

This amino acid replacement may maintain the critical redox functionality of the protein without necessitating the incorporation of selenocysteine

Furthermore, the expression of GPX3 rs736775 in patients undergoing adjuvant chemotherapy with platinum and fluorouracil has been associated with enhanced overall survival (45)