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It belongs to a new generation of incretin-based compounds often called triple agonists because of their ability to simultaneously activate three distinct metabolic receptors: the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R), and the glucagon receptor (GCGR)

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This mechanism is crucial for patients experiencing severe brain fog, sensory overload, and widespread neuropathic pain, as it directly dials down the central nervous system's hypersensitivity

No large human trial has yet clarified its in vivo mechanism, a translational gap flagged in current commentary [6]

CJC-1295 is often combined with Ipamorelin to support healthy growth hormone levels