It was originally identified as a fragment derived from a larger protein found in human gastric juice, which sparked early scientific interest due to its unusual stability and biological activity under experimental conditions
Among patients receiving persistent medication at one year, 61% of patients prescribed semaglutide for obesity achieved at least 10% weight reduction as compared to 23.1% among those prescribed semaglutide for T2D, 28.6% liraglutide for obesity, and 12.3% liraglutide for T2D groups
GLP-1 stands for glucagon-like peptide-1, a hormone your body releases naturally after meals
Following any MHRA marketing authorisation, NICE (the National Institute for Health and Care Excellence) would be expected to conduct a technology appraisal to determine whether retatrutide represents a cost-effective use of NHS resources and to establish guidance on appropriate patient populations
Read: To view or add a comment, sign in A secret shopper survey offers an alarming, if unsurprising, glimpse into the world of telehealth purveyors of GLP-1 medicines
Genes Dev 14(22):28312838
